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EXPERT HUB

PREVENTION

Focussing on the prevention of neurodegenerative diseases and their progression to develop symptoms as observed in dementia

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Expertise

#prevention  #clinicaltrials  #cohorts  #riskfactors  #cognition

Craig is the Professor of Psychiatry of Ageing at the University of Edinburgh, Director of Edinburgh Dementia Prevention and Director of Brain Health Scotland.

Craig is internationally renowned for his work on the design and prosecution of clinical trials. He has been Principal Investigator for almost 30 commercial trials in Alzheimer’s disease, National Chief Investigator for 15 in the UK and Global Coordinating Investigator on 6.

Craig’s research focuses on early detection of disease and the promotion of brain health throughout the life-course to mitigate risks for development and progression of brain diseases that lead to dementia.

Craig is Chair of the Scottish Dementia Research Consortium (SDRC) and Chief Investigator of the European Prevention of Alzheimer’s Dementia (EPAD) Consortium and the PREVENT Dementia Programme.

Prof Craig Ritchie
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Dr Vanessa Raymont

Vanessa is an academic old age psychiatrist working at the University of Oxford with a long standing interest in the late life cognitive effects of traumatic brain injury (TBI), as well as clinical trials in cognitive disorders and dementia.

 

Vanessa leads a number of studies focused on dementia prevention and is part of the Oxford Brain Health Clinic initiative. Vanessa is also director of the Oxford Brain Health Clinical Trials Unit, an associate director for Dementias Platforms UK2 and Dementia and Mental Health Lead for the Thames Valley and South Midlands Clinical Research Network.

Expertise

#clinicaltrials

#braininjury

#TBI

#prevention 

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Dr Lucy Stirland

Lucy is a psychiatrist undertaking specialist training in the care of older people. She is also a researcher, having completed a PhD in epidemiology at the University of Edinburgh in 2020.

 

Lucy's research focuses on people who have many co-existing illnesses, particularly those with a mental illness or dementia. She studies the relationships between these conditions using data both from research studies and from the NHS. In her clinical work, Lucy assesses and treats older people with dementia and mental illnesses in the community and in hospital.

Expertise

#oldagepsychiatry

#multimorbidity

#polypharmacy
 

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Miles Welstead

Miles has a BSc and MSc in psychology which has led onto undertaking a PhD studying the individual differences in the causes and consequences of ageing.

 

In particular Miles is interested in the occurrence of frailty in later life and the risk and preventative factors associated with this.

 

Frailty can affect a vast number of people and being able to identify those who are at highest risk is a crucial step for us to be able to get people on a healthier trajectory with a lower risk of frailty and subsequently a lower risk of disease, disability and death. 

Expertise

#frailty

#cognition

#mildcognitiveimpairment

#longitudinalresearch
 

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Professor Alan Gow

Alan is a Professor of Psychology at Heriot-Watt University, where he leads the Ageing Lab and is Deputy Director of the Centre for Applied Behavioural Sciences. His research focuses on the identification of lifestyle and behavioural factors that predict healthy ageing, primarily cognitive ageing. That is, the factors that might protect or harm the ageing brain. Alan is mainly interested in factors which are modifiable, such as activity participation and exercise, social networks and support, and occupational characteristics and exposures. By being amenable to change, such factors are potential targets for interventions designed to reduce or delay the effect of ageing on cognitive abilities. He is currently developing new community-based interventions within The Ageing Lab where volunteers are supported in taking up new activities to assess the potential benefits of novel engagement and social connection for health and wellbeing.

 

Alan has almost 20 years’ experience researching ageing, including the design and delivery of longitudinal studies and interventions. He has strong working links with the third sector including Age Scotland and Age UK, being the national charities for older people, as well as international research collaborations across Europe and the US. Ensuring research has impact is a key priority for Alan, and he has been an invited contributor to the Global Council on Brain Health, an international collaboration from AARP/Age UK developing expert reports on the lifestyle factors associated with brain health, and the SAPEA report “Transforming the Future of Ageing” which reported to the European Commission in 2019.

Alongside his research, Alan is involved in a number of public engagement and outreach activities to share what we think might benefit brain health as we age, ranging from talks with older people’s groups, performances at the Edinburgh Festival Fringe and contributions to radio/TV. Those activities have been recognised with the British Psychological Society Public Engagement and Media Award in 2016, and as one of two runners-up in the 2019 Nature Research Awards for Driving Global Impact.
 

Expertise

#healthyageing

#cognition

#lifestyle

#riskfactors

#longitudinalresearch
 

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Dr Tim Wilkinson

Tim is a neurologist and clinical lecturer in Edinburgh. He completed his PhD in Epidemiology at the University of Edinburgh in 2020. Tim's research focuses on the use of routinely-collected healthcare datasets (such as primary care and hospital admissions data) to better understand ways in which we can prevent dementia.

 

He co-created the SAIL Dementia e-Cohort (SAIL-DeC). SAIL-DeC is a 'virtual' cohort created from Welsh routine data to facilitate epidemiological dementia research.

Expertise

#routinedata 
#clinicaltrials 
#epidemiology

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Sarah Gregory

Sarah is a part-time PhD student studying the associations between the risk for Alzheimer's disease and HPA axis (stress response) dysfunction in mid and later life.

Sarah has a BSc in Psychology and an MSc in Mental Health Science Research.

Sarah also works as a study coordinator with over 10 years of experience managing complex interventional and observational studies in mental health, dementia, mild cognitive impairment and healthy ageing.

Expertise

#cohorts 
#stress

#clinicaltrials 
 

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Expertise

#statistics 
#epidemiology

#healthyageing
 

Dr Graciela Muniz Terrera

Graciela is a Senior Lecturer in Biostatistics and Epidemiology at the Centre for Dementia Prevention where she works in collaboration with colleagues in the EPAD (European Prevention of Alzheimer's Dementia) and the IALSA (Integrative Analysis of Longitudinal Studies of Ageing) network of longitudinal studies of ageing and dementia.

Before working in Edinburgh, Graciela was a Lecturer at UCL and Programme Leader Track at the MRC Lifelong Health and Ageing Unit and also worked for several years in Cambridge at the MRC Biostatistics Unit, where she also did her PhD. Her research has been supported by an MRC Career Development Award in Biostatistics, the Alzheimer's Society and the IALSA Programme Grant from the US National Institute of Health.

She has extensive experience developing and applying  longitudinal methods to gain a better understanding of ageing and dementia. She is also interested in harmonisation methods for evidence synthesis and reproducible research.

DIAGNOSIS

Research to discover or improve methods to allow neurodegenerative diseases to be detected earlier and more accurately.

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FUNDAMENTAL SCIENCE

The foundation for the development of 

effective treatments for neurodegenerative diseases

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LIVING WITH DEMENTIA

Improving our understanding of all aspects of dementia care and caring

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INFORMATICS

Coordinated approach to integrate neurodegenerative diseases data from all real world clinical and research sources  across Scotland

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